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How to fight an excessive cholesterol

Excessive cholesterol harms our health. There is good cholesterol that cleans our arteries, and a bad one that provokes the risk of a heart attack or stroke.

Approximately 80 percent of cholesterol is produced in the liver, the rest is ingested from food. To find out if it is dangerous for the body, it is necessary to take a blood test for lipoproteins every year.

If a person reveals changes of indicators, he can adjust the diet on time. Research on lipoproteins is important for those who are at high risk of atherosclerosis, have coronary heart disease, endocrine pathologies, diseases of the liver, kidneys, metabolism, diabetes. The study is conducted to monitor the effectiveness of statin therapy.

To regulate the level of cholesterol in the blood, remember that saturated fats increase the level of “harmful” cholesterol, and polyunsaturated fats, on the contrary, reduce it and increase the amount of “useful”. What products are most beneficial in this case?

  • Avocado

Avocados are the best source of monounsaturated fats, it clears blood vessels from cholesterol and makes their walls stronger. This fruit will help moisturize the skin, strengthen nails and hair and will be an excellent addition to a breakfast, lunch or dinner.

  • Salmon

This fish contains Omega-3 fatty acids, which help strengthen the walls of blood vessels, prevent the formation of atherosclerotic plaques, enrich the body with iodine and vitamins B1 and B2, improving metabolism.

  • The nuts

Nuts contain minerals, vitamins, easily digestible protein, a large number of calories that can perfectly saturate the body, and healthy fats that reduce cholesterol levels in the blood.

  • Spinach

Spinach leave is a source of iron, potassium, magnesium, fiber, vitamins K and B and antioxidants. Spinach is very low-calorie product, but it perfectly nourishes and gives vitality. This product also reduces the risk of heart disease and plaque formation, successfully fights cholesterol and its effects.

  • Beans

Beans contain fibers that lower the level of “bad” cholesterol. 100 grams of beans improve the condition of blood vessels, saturate with vitamins, minerals, and fiber, stabilize blood sugar levels, remove harmful preservatives from the body and saturate it with protein.

  • Tea

Tea contains many antioxidants in its composition, thanks to which the metabolism improves, the work of all internal organs is normalized. Also, tea, especially green tea, significantly affects the level of cholesterol in the blood, reducing harmful and increasing beneficial one.

  • Olive oil

Olive oil is a superfood for those who suffer from diseases of the heart or blood vessels. If cholesterol is elevated, it is recommended to take up to 2 tablespoons of olive oil per day. You should also replace them with the usual sunflower oil in salads and dressings.

  • Garlic

Garlic is a universal remedy for many diseases. In addition to the fact that it kills bacteria and copes with various inflammations, it also reduces the level of bad cholesterol in the blood and helps the heart to work.

The innovation of super antibiotic

The real problem nowadays is that bacteria have become immune to antibiotics. This is due to the fact that we receive antibiotics with food (for example, the meat of industrial production), due to the mutation of bacteria and also the appearance of new infections that are resistant to modern medicines. At the same time, a new series of antibiotics was last time invented back in 1987.

Now scientists have discovered a completely new class of antibiotics, which consists of 25 antimicrobial components. It is important that diseases cannot adapt to it and develop resistance. An international group of microbiologists was able to find a new source of antibiotics. They abandoned bacteria that were easily grown in the laboratory and learned to cultivate rare members of the underground microflora using an iChip device that allows them to grow cells directly in the natural conditions of the soil.

Especially effective against such dangerous diseases as tuberculosis and Staphylococcus aureus is “teixobactin”. Indeed, in vitro tests have shown that neither Staphylococcus aureus or tuberculous mycobacterium under the influence of teixobactin could form a single bacterium resistant to it.

What is the reason for his superpower? A new antibiotic spoils the cell wall of microbes, but its specific target is not at all the enzyme that is responsible for one or another stage of its assembly, and not the peptide that compose it. Teixobactin binds to the precursors of peptidoglycan and teichoic acid, which build the cell wall. The antibiotic interacts with a very conservative area in polymer structures. It is so conservative that no bacteria have been able to find any modifications in it.

Usually, if a medicament enters a structural protein or protein-enzyme, the microbes use mutations that alter the structure of the protein so much that it continues to do its job but becomes insensitive to the antibiotic. However, in this case, the substance is aimed against extremely important molecular complexes that do not tolerate any mutations. In other words, there is no way to change the enzymes that are responsible for this area of the cell wall so that it (a piece of polymer) becomes invisible to the antibiotic.

A similar mechanism of action can be found in vancomycin, but it binds to the peptide component of the cell wall, which can be changed without harming the cell. What did the bacteria: for almost 30 years we have been dealing with vancomycin-resistant microbes that have mutated the menionned peptide.

The bacterium itself, which produces teixobactin, is designed in such a way that it does not need to defend against its own antibiotic, there are no targets in its cell wall. Most likely, there are no ready-made genes against teixobactin in nature, and it is simply impossible to acquire resistance to it due to the horizontal transfer of the desired gene from one bacterium to another. It is possible that the resistance to teixobactin will still appear, but it will take much longer time than usual.

Angelman syndrome – Symptoms and causes

Angelman syndrome - Symptoms and causes

With recent advances in medical science, there have been many genetic diseases that have come to the attention of doctors and health experts. Of these, a genetic disorder caused by certain defects on chromosome 15 is the Angelman syndrome. Scientists and researchers have suggested many different ways to help cure the disease, but so far there are no treatments backed by evidence and concrete results. Angelman syndrome is known to induce spasmodic movements, as well as a sunny appearance in person. This defect is also called AS

More about the Angelman syndrome — Symptoms and causes

Because the developmental problems associated with the genetic structure are unclear during the early years, the Angelman syndrome is not detected or confirmed at birth or even in childhood. The age of three to seven years is the most common age when most children begin to show obvious symptoms of the disorder.

Even so, Angelman syndrome is not a comprehensible and well understood disorder. This is the main reason why this disorder can only be confirmed when the parents read it or see it in another child, with their own eyes. Many of the symptoms can be attributed to Angelman syndrome in children who have The sad part is that most of these symptoms remain dormant for a long period of time and appear only at a certain age, which makes the discovery of Angelman syndrome a difficult task.

Causes of the disorder

Angelman syndrome is brought about by an abnormal expression of a group of genes on chromosome 15. The researchers found a very small area removed on this chromosome in patients with the syndrome.

This deleted region contains genes that can be activated or deactivated, depending on the parent where the chromosome has been inherited from The gene for this disease is called UBE3A. When this gene is activated, The syndrome does not occur. However, when it is turned off or lost, Angeman syndrome occurs. In patients with Angelman syndrome, the UBE3A gene occurs only on the chromosome given by the mother.

Symptoms

Medical scientists and researchers confirm some of the symptoms that can be attributed to the syndrome in almost all patients. These may include irregular body movements, poor pronunciation and weird behaviors in children. Regardless of the general symptoms and the more ambiguous symptoms, there are other symptoms that may not be noted at first.

These can include abnormalities in the EEG, abnormal development and growth of the baby’s head, seizures and many more All these superficial symptoms show out before the age of three years in children with the disease.

Conclusion

Since no solid methods have been found to prevent or stop the disease, there are no standardized ways to treat or prevent this genetic disease. Most of the curative and preventive measures are aimed at solving the problem at hand and help with the balance and walk.

This is done through the use of adaptive devices and physiotherapy. Language assessment and appropriate speaking skills are important at an early age, which can help improve the child’s situation. Parents of children with this disorder can seek a lot of information, assistance and support from different communities and support groups.

Possible Treatment for Angelman Syndrome

Possible Treatment for Angelman Syndrome

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